You cannot close MS Word application by:

The question asks which option cannot be used to close the entire MS Word application. Understanding the difference between closing a document and closing the application is crucial.

• "From File menu choose Close submenu" is the correct answer because this action typically closes only the currently active document, leaving the MS Word application itself open. You would still see the Word interface, ready to open a new document or work on another.
• "Choosing File menu then Exit submenu" is a direct command to terminate the application.
• "Press Alt + F4" is a universal Windows shortcut to close the active application window.
• "Click X button on title bar" is the standard graphical user interface method to close any application window.

Therefore, 'Close' only affects the document, while 'Exit' or the other methods close the program.