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In the context of Human Biology, what is the ‘Telomere’ and why is it significant in aging?

A. A brain cell that stops functioning
B. Protective caps at the end of chromosomes that shorten as cells divide.
C. A stomach enzyme that breaks down proteins
D. A type of white blood cell
Correct Answer: B. Protective caps at the end of chromosomes that shorten as cells divide.
Explanation:


The correct answer is Protective caps at the end of chromosomes that shorten as cells divide. because telomeres prevent DNA degradation, acting as a biological clock for aging cells.



    • Step 1 (Structural Protection): Telomeres consist of repetitive, non-coding DNA sequences (TTAGGG) found at the tips of chromosomes, functioning like plastic aglets on shoelaces to keep genetic strands from unraveling or fusing.

    • Step 2 (The Hayflick Limit): Due to the end-replication problem, telomeres shorten slightly with each round of cell division. When they become critically short, the cell hits its replication limit, triggering senescence or programmed death.

    • Incorrect Options:

      • A brain cell that stops functioning is incorrect because senescent neurons describe dying or degraded nervous system tissue, not a chromosome structure.

      • A stomach enzyme that breaks down proteins is incorrect because protein-digesting enzymes in the stomach are classified as proteases, such as pepsin.

      • A type of white blood cell is incorrect because immune defense cells traveling through the bloodstream are called leukocytes (such as lymphocytes or neutrophils).




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