Dars-e-Nizami was established during the reign of:

The Dars-e-Nizami is a comprehensive curriculum for Islamic education widely used in traditional madrasas across South Asia. This standardized system of learning was primarily established and gained prominence during the reign of the Mughal Emperor Aurangzeb (1658-1707). It was systematized by Mulla Nizamuddin Sehalvi of Firangi Mahal, who lived during Aurangzeb's era, providing a structured approach to religious and rational sciences.

The other emperors mentioned are incorrect:

• Akbar, Humayun, and Jahangir were earlier Mughal rulers. The Dars-e-Nizami curriculum was not formulated or widely adopted during their respective reigns.